Background:
The National Institute for Medical Research (NIMR) is a parastatal organization established by an Act of parliament No. 23 of 1979 (CAP. 59, R.E. 2002) and became operational in 1980. NIMR-Muhimbili Research Centre is one of the NIMR Centres located in Dar es Salaam. The Centre is currently conducting research on HIV/AIDS, Tuberculosis, non-communicable diseases (NCDs) as well as other diseases of public health importance. The Centre is looking for qualified, experienced and well-motivated personnel to fill the following vacant positions whose duty station will be in Dar es Salaam Region.
NIMR is collaborating with the Drugs for Neglected Diseases initiative, a Swiss foundation having its registered office at 15, chemin Camille-Vidart, 1202 Geneva, Switzerland (“DNDi”); St George’s Hospital Medical School,UK; FARMOVS (Pt) Ltd, South African; Luxembourg Institute of Health, Luxembourg and Lilongwe Medical Relief Fund Trust – Malawi to conduct an open-label, randomized, controlled parallel-group trial to evaluate the comparative bioavailability, efficacy and safety of sustained-release flucytosine versus immediate-release flucytosine in adults with cryptococcal meningitis. The study will be conducted in two regional referral Hospital in Dar es salaam, Tanzania.
We have exciting and challenging opportunities for one Assistant study coordinator, one study doctors, two research nurses, one laboratory technician and one internal quality officer to join the NIMR research team, evaluating the impact of slow release Flucytosine. The post holders will be based in Dar es Salaam.
JOB POSITIONS: Study Doctors ( 1post)
PROJECT TITLE: 5FC-HIV project
REPORTING: Project Investigator.
DUTIES AND RESPONSIBILITIES:
- Day to day running of clinical trial (site coordination)
- Communication between ward staff and study staff
- Screening, enrolment and randomisation of study patients
- Day to day clinical management of patients & OPD management of patients after discharge
- Reporting any SAEs and SUSAR immediately to the local PI
- Completing AE forms within of their occurrence and communicating the AE/SAE/SUSAR to the local and international PI
- Completing progress reports for the DSMB/TSC and ethics committees
- Liaising with the study investigator in ordering trial equipment
- Ensuring case report forms (CRFs) are kept accurate and up to date
- Ensuring CRFs and AE forms are filled & faxed using the EDC or ODK
- Checking and recording all laboratory and radiology results for trial patients.
- Laboratory transport and storage of samples: serum, urine and plasma (in conjunction with laboratory technician)
- Follow-up of study patients for ten weeks from date of admission (enrolment)
- Responsible for ensuring secure storage and sufficient supplies of IMP and consumables in conjunction with pharmacist
- Ensure appropriate laboratory specimen collection, storage and sample shipping as required
- Preparation for external monitoring visits
- On-site monitoring of trial (laboratory, pharmacy, clinical areas, data entry)
- Provides accurate and timely data collection, documentation, entry, and reporting in both sponsor and study database
- And carry out any other related duties as may be assigned by the supervisor
QUALIFICATION AND COMPETENCE:
- Valid registration practice licence
- Bachelor of Medicine (MD) or equivalent knowledge
- Demonstrable commitment to improving the lives of Cryptococcal meningitis patients;
- Excellent written and oral communication skills in both English and Kiswahili;
- To work as part of a multidisciplinary research team; and Computer literacy.
- Experience to work with research organization or research institution.
- Ability to prepare comprehensive project documentation and reporting, using MS Office software, for internal and stake holders’ communication.
- Previous two years’ experience in the field of clinical trials, and knowledge of good clinical practice would be highly desirable; and/or previous experience in Project Management will be an added advantage
TERMS OF SERVICE:
One-year contract which may be renewed on the basis of performance and mutual agreement
DUTY STATION:
The successful candidate will be based at NIMR – Muhimbili Centre.
COMPENSATION:
A competitive salary will be offered as per project budget.
MODE OF APPLICATION:
- Application letters should be written in English.
- Applicants should indicate three reputable referees with their reliable contacts.
- Applicants must attach their detailed relevant certified copies of academic certificates including form four certificates.
- Application letters should be attached with detailed curriculum vitae.
- Closing date for applications is 15th July, 2024.
- All applications should be addressed to:
Centre Manager,
National Institute for Medical Research (NIMR), Muhimbili Centre,
Muhimbili University for Health and Allied Sciences
Off United Nation Road, Maliki Road-Upanga, Plot 1048/5
4th Floor Haile Debas Centre for Health Professional Building (CHIPE)
P.O. Box 3436,
Dar es Salaam.